Plateau technique de Neuro-Imagerie

Plateau technique de neuro-imagerie

: neuroimagerie.lppa AT college-de-france.fr

Presentation
Research projects
Publications

Presentation

The tri-dimensional neuro-imagery platform performs quantitative neuro-anatomic analysis, numeric biological pictures and allows for 3D reconstruction of axons or neural ways which can be displayed using the Neurolucida software (Microbrightfield Co).
The neuro-imagery platform has been used for the past few years by several members of the IFR 52 (LPPA, Neuropharmacology lab & DPRN lab) either for their own studies or for common projects with the IFR.
This platform acquired a second high tech microscope equipped with the Neurolucida system (for 3D reconstruction) and a virtual slice module which allows for the display of an entire anatomical image from several images observed through a high resolution microscope (2005).

Animation 3D (AVI - 2 M°)

Research projects in which the tri-dimensional neuro-imagery platform is used (list is non-exhaustive) :

Etude des circuits neuronaux du mouvement des yeux.
W Graf & A. Grantyn - laboratoire LPPA
Recherche d'1 asymétrie de l'intégration interhémisphérique visuelle via le corps calleux en cas de strabisme.
C. Milleret – laboratoire LPPA
Spécificité d'orientation des connexions interhémisphériques dans le cortex visuel : étude anatomique et fonctionnelle par imagerie optique.
C. Milleret – laboratoire LPPA
Distribution des astrocytes marqués en GFAP, connexines 30 et 43 au cours du développement.
C. Milleret & C. Giaume - laboratoires LPPA et Neuropharmacologie

Sample of publications

2005

E. Buiquoc, N. Quenech’du and C. Milleret (2005) Plasticity of visual interhemispheric transfer to areas 17 and 18 in cats with convergent unilateral early strabismus. (Association of Research in Vision and Ophthalmology – floride – communication affichée)
N. Rochefort, P. Buzas, A. Koza, N. Quenech’du, U.T. Eysel, C. Milleret and Z.F. Kisvarday (2005) Fonctional specificity of callosal connections in the cat visual cortex (en cours)
N. Rochefort, N. Quenech’du, P. Ezan, C. Giaume and C. Milleret (2005) Postnatal development of GFAP, Connexins43 and 30 in the primary visual cortex of normal and monocularly deprived cats Brain Research (sous presse)

2002

W. Graf, N. Gerrits, N. Yatim-Dhiba and G. Ugolini (2002) Mapping the oculomotor system : the power of transneuronal labeling with rabies virus. Eur. J. Neurosci. 15(9) : 1557-1562
A. Grantyn, A.M. Brandi, D. Dubayle, W. Graf, K. Hadjidimitrakis and A. Moschovakis (2002) Density gradients of trans-synaptically labeled collicular neurons after injections of rabies virus in the lateral rectus muscle of the rhesus monkey. J. Comp. Neurol. 451(4) : 346-61