Contacter le Webmestre |
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Gabrielle Girardeau
Ph.D. student
Tel : (00 33) 1 44 27 12 93
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gabrielle.girardeau AT college-de-france.fr
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Presentation
My PhD work aims at understanding the mechanisms underlying memory consolidation during sleep in rats. I'm especially interested in the physiological rhythms of hippocampus and neocortex and their interactions, during slow-wave sleep. The in vivo electrophysiology techniques used in our lab allow the recording of local-field potentials and large neuronal ensembles, on freely-behaving animals. I thus can study neuronal activity in various parts of the brain during learning tasks and sleep/rest of the animals. Within the team « Memory and Spatial navigation », I recently published a study showing the causal role of rapid hippocampal oscillations in memory consolidation.
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Skills
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In vivo electrophysiology : construction of headstages supporting multiple wire electrodes and multi-site silucium electrodes, implantation surgeries, recordings.
Behavior : Animal training on spatial memory tasks.
Electrophysiological and behavioral data processing and analysis : data treatment and spike sorting (Neuroscope, Klusters, NDManager), programming (matlab). |
Publications & Teaching
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G. Girardeau, M.B. Zugaro Hippocampal ripples and memory consolidation. Current Opinion in Neurobiology, doi:10.1016/j.conb.(2011).02.005.
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G. Girardeau , K. Benchenane, S.I. Wiener, G. Buzsáki & M.B. Zugaro, Selective suppression of hippocampal ripples impairs spatial memory, Nature Neuroscience (2009) 12, 1222-3.
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S. Herwik, S. Kisban, A.A.A. Aarts, K. Seidl, G. Girardeau , K. Benchenane, M.B. Zugaro, S.I. Wiener, O. Paul, H.P. Neves & P. Ruther, Fabrication technology for silicon-based microprobe arrays used in acute and sub-chronic neural recording, Journal of Micromechanics & Microengineering (2009) 19.
Teaching
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